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Linearization of EBT3 film dose response and virtual film dosimetry for SBRT quality assurance

机译:EBT3薄膜剂量响应和虚拟薄膜剂量测定的线性化,用于SBRT质量保证

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摘要

EBT3 film offers high spatial resolution and low energy dependence, making it a suitable choice for quality assurance where high dose gradients are present, such as the case for SBRT. This work presents a simple method to adjust scanner settings so that dose response becomes linear. This linearity eliminates the need to obtain a calibration curve and associated uncertainties in curve fitting. Relative dosimetry can be performed after dose normalization to a reference point. Linearity is also a more robust condition than calibration curve with respect to scanner warm-up conditions, resulting in reduced uncertainty in dose measurement. An in-house developed program reads the film scan and a 2D dose map then constructs both to virtual films using grayscale values. Film intensity value was normalized to dose at reference point. Relative dosimetry was performed by comparing the two resulting images. Patient specific quality assurance was conducted for two SBRT cases. In both plans more than 95% gamma function points passed the gamma criteria of 2%/3mm.
机译:EBT3膜具有高空间分辨率和低能量依赖性,使其成为存在高剂量梯度的质量保证的合适选择,例如SBRT。这项工作提出了一种调整扫描仪设置的简单方法,以使剂量响应变为线性。这种线性消除了在曲线拟合中获得校准曲线和相关不确定性的需求。在剂量归一化至参考点后,可以进行相对剂量测定。对于扫描仪预热条件,线性也比校准曲线更稳定,从而减少了剂量测量的不确定性。内部开发的程序读取胶片扫描和2D剂量图,然后使用灰度值将两者构建为虚拟胶片。将膜强度值标准化为参考点的剂量。通过比较两个所得图像进行相对剂量测定。针对两个SBRT病例进行了针对患者的质量保证。在这两个计划中,超过95%的伽玛功能点通过了2%/ 3mm的伽玛标准。

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